HYBRIDknife® flex

Elevating 3rd space endoscopy

Precise application in complex thin-walled anatomy

Benefit from an all-in-one solution uniting cutting-edge technology with new flexibility. Inject, cut, coagulate – no need for instrument exchange - for efficient workflow and ease of use.

INJECT NEEDLE-FREE

Expand the submucosal space without instrument exchange using high-pressure, needle-free, tissue-selective hydrodissection.

CUT AND COAGULATE PRECISELY

Achieve high electrosurgical precision with limited thermal damage using the thin electrode, and apply various coagulation techniques with VIO® modes.

FLEX WITH STABILITY

Expect smooth passage and stable electrode length, even in difficult angled or retroflexed endoscopic positions.

Unmatched synergy

Hybrid Technology: combining hydrodissection and electrosurgery

ELECTROSURGICAL PRECISION

  • Thin 0.5 mm electrode for precise cutting with limited thermal damage
  • Especially important for thin-walled anatomy, e.g. right colon
  • Various distal tip designs for a range of electrosurgical cutting, coagulation, and tissue manipulation techniques

HIGH-PRESSURE INJECTION

  • More consistent and reliable separation and expansion of the submucosal tissue plane versus conventional injection needle, even in challenging anatomy, e.g. over a fold or submucosal fibrosis
  • Isolate and expose vasculature, and compress blood vessels, reducing the risk of bleeding

New scientific publications

Colorectal Endoscopic Submucosal Dissection: Performance of a Novel Hybrid-Technology Knife in an Animal Trial

Jacques, J.; Neuhaus, H.; Enderle, M.D.; Biber, U.; Linzenbold, W.; Schenk, M.; Khalaf, K.; Repici, A.

PUBLICATION LINK

Safety and performance of the HYBRIDknife flex in a porcine model of esophageal endoscopic submucosal dissection: A pilot study

Khor, C.J.L.; Ichimasa, K.; Tsao, S.K.K.; Biber, U.; Saito, Y.

PUBLICATION LINK

The HybridKnife family

High-pressure, needle-free, tissue-selective hydrodissection
HybridKnife®
HYBRIDknife® flex

What experts say...

“... we are presenting the main features that are going to change the way to do ESD in 3rd space endoscopy, using these absolutely new and incredible HYBRIDknife® flex. “ 

Prof. Alessandro Repici during the Endoscopy on Air event: Advancing the Future of ESD for Early GI Neoplasia
Prof. Alessandro Repici during the Endoscopy on Air event: Advancing the Future of ESD for Early GI Neoplasia
96%

are satisfied with the performance of HYBRIDknife® flex

95%

are likely to replace thir current instrument with HYBRIDknife® flex

98%

are likely to recommend HYBRIDknife® flex to colleagues

*Based on user acceptance test 2023

Powered by VIO® 3

Tailor your own technique

Equipment

The HYBRIDknife® flex unites electrosurgery with high-pressure hydrodissection. Powered by the GI workstation, the instrument provides high-pressure injection and precise electrosurgical application. Proprietary algorithms and state-of-the-art microprocessor technology with measurements on target tissue at more than 25 million per second for reliable, reproducible, and homogeneous tissue effects.

MORE INFO ABOUT VIO GENERATORS

Electrosurgical modes

Achieve the desired tissue effect by choosing the appropriate mode for the interventional technique e.g.,

  • endoCUT®
  • preciseSECT®  
  • softCOAG
  • dryCUT

Selection of up to 6 sub-programs can be achieved directly from the procedural field via ReMode® button.

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